| 发明名称 |
PROCESS FOR THE PREPARATION OF HIGHLY PURE RABEPRAZOLE SODIUM SALT |
| 摘要 |
<p>A method for the preparation of (±)-sodium-2-[[[4-(3- methoxypropoxy)-3- methyl-pyridinyl]methyl]sulfinyl]-1H-benzimidazole(Rabeprazole sodium) of formula (I), which comprises dissolving Rabeprazole of Formula (II) in aqueous sodium hydroxide until complete dissolution has taken place and thereafter subjecting the so obtained solution to lyophilization to obtain highly pure Rabeprazole sodium of Formula (I) in dry form.</p> |
| 申请公布号 |
WO03101452(A8) |
申请公布日期 |
2004.03.11 |
| 申请号 |
WO2003IN00208 |
申请日期 |
2003.06.02 |
| 申请人 |
AUROBINDO PHARMA LTD.;RAMESH, DANDALA;MEENAKSHISUNDERAM SIVAKUMARAN;U. K. RAY |
发明人 |
RAMESH, DANDALA;MEENAKSHISUNDERAM SIVAKUMARAN;U. K. RAY |
| 分类号 |
A61K31/4439;C07D401/12;(IPC1-7):A61K31/443;A61K9/19 |
主分类号 |
A61K31/4439 |
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