Gene encoding abc-1 paralogs and the polypeptides derived therefrom

摘要

The present invention relates to three novel genes and polypeptides derived therefrom encoding "PD-ABC" proteins. The invention also describes methods for using the novel gene and polypeptides in the detection of genetic deletions of the gene, subcellular localization of the polypeptide, binding assays in connection with the chemical databases, gene therapy, and identification of chemicals which may be used in the therapeutic treatment of PD-ABC-mediated diseases.