发明名称 Caspase-1 inhibitors and methods for their use
摘要 The invention provides compounds of Formula I and derivatives thereof, pharmaceutical compositions comprising a compound of Formula I, and methods of treatment utilizing such compounds and compositions: wherein: R1 is chosen from optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; L is a linker; R2 is chosen from optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; and or single stereoisomers, mixtures of stereoisomers, or the pharmaceutically acceptable salts, amides, or esters thereof.
申请公布号 US2004048895(A1) 申请公布日期 2004.03.11
申请号 US20030456458 申请日期 2003.06.05
申请人 ALLEN DARIN;FAHR BRUCE;OSLOB JOHAN;RAIMUNDO BRIAN C.;ROMANOWSKI MICHAEL J. 发明人 ALLEN DARIN;FAHR BRUCE;OSLOB JOHAN;RAIMUNDO BRIAN C.;ROMANOWSKI MICHAEL J.
分类号 C07C237/22;C07C311/29;C07D213/56;C07D241/44;C07D263/54;C07D307/79;C07D333/24;C07D333/34;C07D409/12;C07D409/14;C07D413/12;(IPC1-7):A61K31/443;A61K31/402;A61K31/198;C0745/02 主分类号 C07C237/22
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