| 摘要 |
Buccal aerosol sprays or capsules using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal polar compositions of the invention comprise formulation (I): aqueous polar solvent, active compound, and optional flavoring agent; formulation (II): aqueous polar solvent, active compound, optionally flavoring agent, and propellant; formulation (III): non-polar solvent, active compound, and optional flavoring agent; and formulation (IV): non-polar solvent, active compound, optional flavoring agent, and propellant. |
