发明名称 GENETICALLY MODIFIED MICRO ORGAN EXPLANT, METHOD FOR PRODUCING THE SAME AND ITS APPLICATION
摘要 <P>PROBLEM TO BE SOLVED: To provide a method for inducing vascularization in mammal organization. <P>SOLUTION: The genetically modified micro organ explant manifests at least one recombinant DNA product, wherein the micro organ explant contains a cell group and keeps a microstructure and a three-dimensional structure of the original organ and has a size selected to minimize death caused by cytotoxicity, excrement accumulation and insufficient nutrient by diffusing sufficient nutrients and gas into cells in the micro organ explant and diffusing cell excrements from the micro organ explant, and some cells of the group of the micro organ explant cell manifest micro organ explant expresses at least one recombinant gene product. <P>COPYRIGHT: (C)2004,JPO
申请公布号 JP2004073206(A) 申请公布日期 2004.03.11
申请号 JP20030305960 申请日期 2003.08.29
申请人 YISSUM RESEARCH DEVELOPMENT CO OF THE HEBREW UNIV OF JERUSALEM 发明人 MITRANI EDUARDO N
分类号 A61K35/23;A61K35/12;A61K35/26;A61K35/28;A61K35/34;A61K35/36;A61K35/37;A61K35/39;A61K35/407;A61K35/42;A61K35/44;A61K35/48;A61K48/00;A61L27/38;A61P1/18;A61P7/00;A61P9/00;A61P17/00;A61P27/02;A61P35/00;A61P43/00;C12N5/00;C12N5/08;C12N5/10;C12N15/09;C12N15/85 主分类号 A61K35/23
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