Method for treating neoplastic cells using cycloprodigiosin or salt thereof

摘要

Neoplastic cells are treated by examining whether a potential subject has neoplastic cells in which Rb is present and NF-kappaB and/or AP-1 are constitutively being activated and then administering cycloprodigiosin or a pharmaceutically acceptable salt thereof in an amount effective to suppress Rb phosphorylation and to suppress transcriptional activity of NF-kappaB and/or AP-1 which are constitutively being activated, to the potential subject. Alternatively, an autoimmune disease is treated by examining whether a potential subject has said autoimmune disease caused by gene expression which depends on binding to the CRE sequence and then administering cycloprodigiosin or a pharmaceutically acceptable salt thereof in an effective amount to said potential subject.