| 摘要 |
The present invention pertains to an antibiotic polymer combination/antibiotics polymer combination that ensures the continuous release of antibiotics over a period of several days under physiological conditions, and that can be used in human and veterinary medicine. The surprising finding that forms the basis of the invention is that one or more antibiotic salts, which are sparingly soluble in water, from the groups comprising aminoglycoside antibiotics, lincosamide antibiotics, tetracycline antibiotics, glycopeptide antibiotics, quinolone antibiotics and chlorhexidine, are suspended [sic; are suspended in] homogeneous polymer mixtures, which comprise one or more hydrophobic, nonionic polymers from the groups comprising polyvinyl chloride), post-chlorinated polyvinyl chloride), poly(vinylidene chloride), polyvinyl fluoride), poly(vinylidene fluoride) and copolymers comprising vinyl chlorid e and one or more nonionic monomers, and which comprise one or more hydrophilic polymers from the groups comprising polyethers, and this suspension forms composites that exhibit the release of an active ingredient over a period of days in an aqueous medium.
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