发明名称 |
ESTRADIOL-CONTAINING PLASTER |
摘要 |
PROBLEM TO BE SOLVED: To provide an external plaster whose adhesive layer has improved solubility for estradiol and/or its derivative contained in the adhesive layer as an active ingredient, in whose support the active ingredient is not adsorbed, and which itself can follow the uneven surface or movement of skin. SOLUTION: This estradiol-containing plaster comprising the support and the adhesive layer is characterized by preparing the adhesive layer from an acrylic adhesive containing 0.01 to 1 wt. % of an isocyanate-based cross-linking agent as an essential component, and containing the estradiol and/or its derivative as the active ingredient, 0.1 to 10 wt. % of crotamine and 0.1 to 10 wt. % of oleic acid. COPYRIGHT: (C)2004,JPO
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申请公布号 |
JP2004075537(A) |
申请公布日期 |
2004.03.11 |
申请号 |
JP20020233469 |
申请日期 |
2002.08.09 |
申请人 |
TEIKOKU SEIYAKU CO LTD;FUSO PHARMACEUTICAL INDUSTRIES LTD |
发明人 |
SUGAWARA TAKAYA;SHIRAI SADANOBU;YAMAJI MASAHIRO |
分类号 |
A61K9/70;A61K31/565;A61K47/12;A61K47/16;A61K47/32;A61P3/06;A61P9/10;A61P15/12;A61P19/10;A61P25/28;C07J1/00;(IPC1-7):A61K31/565 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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