发明名称 Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
摘要 The present invention provides methods and compositions for the treatment of fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH.
申请公布号 US2004047857(A1) 申请公布日期 2004.03.11
申请号 US20030647371 申请日期 2003.08.25
申请人 PILON APRILE L.;WELCH RICHARD W.;FARROW JEFFREY;MELBY JAMES;WIESE LAURA;LOHNAS GERALD 发明人 PILON APRILE L.;WELCH RICHARD W.;FARROW JEFFREY;MELBY JAMES;WIESE LAURA;LOHNAS GERALD
分类号 A61K8/64;A61K8/98;A61K38/00;A61K38/17;A61Q17/00;A61Q19/00;C07K14/47;C07K14/705;C12N15/85;(IPC1-7):A61K39/395 主分类号 A61K8/64
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