发明名称 |
MEMBRANE POTENTIAL CHANGER AND DEATH-INDUCING COMPOSITION FOR APLYSIA NEURON, CONTAINING HYDROGEN PEROXIDE |
摘要 |
PURPOSE: A membrane potential changer of an aplysia neuron containing hydrogen peroxide and a cell death-inducing composition of the aplysia neuron containing the membrane potential changer are provided. Use of the composition induces a change in membrane potential and cell death of the aplysia neuron and thus can provide a model useful for the study of memory and learning. CONSTITUTION: The membrane potential changer of an aplysia neuron contains hydrogen peroxide in the range concentration of 0.01 to 10mM. The cell death-inducing composition of the aplysia neuron contains the membrane potential changer of the aplysia neuron. A change in membrane potential is hyperpolarized in the early time after hydrogen peroxide treatment and then depolarized after then. The aplysia is an Aplysia kurodai captured in a costal area of The East Sea of Korea.
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申请公布号 |
KR20040020225(A) |
申请公布日期 |
2004.03.09 |
申请号 |
KR20020051753 |
申请日期 |
2002.08.30 |
申请人 |
SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION |
发明人 |
KANG, BONG GYUN;KIM, SU DONG |
分类号 |
A61K31/327;(IPC1-7):A61K31/327 |
主分类号 |
A61K31/327 |
代理机构 |
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地址 |
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