METHOD AND APPARATUS FOR DETERMINING THE HOMOGENEITY OF A GRANULATION DURING TABLETING
摘要
An apparatus for detecting the homogeneity of a pharmaceutical mixture has a hopper (10) for containing a mixture of two or more pharmaceutical components and that is situated within a production line of preparation of a pharmaceutical dosage form. A spectroscope (20) is mounted to the hopper (10) for measuring spectroscopic characteristics of the mixture, and a processing device (32) that is not physically coupled to the spectroscope analyzes the spectroscopic characteristics of the mixture and derives information regarding the homogeneity of the mixture. The spectroscope wirelessly sends the spectroscopic characteristics to the processing device (32), which derives information regarding the homogeneity of the mixture. The wireless transmission of the spectroscopic characteristics can be done through infrared radiation or near infrared radiation, and the spectroscopic characteristics can be converted to digital signals prior to being transmitted.
申请公布号
WO03087740(A9)
申请公布日期
2004.03.04
申请号
WO2003US10441
申请日期
2003.04.03
申请人
EURO-CELTIQUE, S.A.;GEHRLEIN, LANE;CIURCZAK, EMIL;RITCHIE, GARY;BYNUM, KEVIN, C.
发明人
GEHRLEIN, LANE;CIURCZAK, EMIL;RITCHIE, GARY;BYNUM, KEVIN, C.