发明名称 Bensóþíasepín og bensóþíadíasepínafleiður með tálmavirkni gegn dausgarnargallsýruflutningi (ileal bile acid transport, IBAT) til að meðhöndla fitudreyra
摘要 The present invention relates to compounds of formula (I) wherein R<SUP>v</SUP>, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>x</SUP>, R<SUP>y</SUP>, M, R<SUP>z</SUP>, v, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5 </SUP>and R<SUP>6 </SUP>are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.
申请公布号 IS7170(A) 申请公布日期 2004.03.04
申请号 IS20040007170 申请日期 2004.03.04
申请人 ASTRAZENECA AB 发明人 INGEMAR STARKE;MIKAEL ULF JOHAN DAHLSTROM;DAVID BLOMBERG;SUZANNE ALENFALK;TORE SKJARET;MALIN LEMURELL
分类号 A61K;A61K31/192;A61K31/397;A61K31/40;A61K31/505;A61K31/554;A61K31/695;A61K31/785;A61P;A61P3/06;A61P7/02;A61P9/00;A61P9/04;A61P9/06;A61P9/08;A61P9/10;A61P17/02;A61P31/00;A61P43/00;C07D;C07D281/02;C07D281/10;C07D285/36;C07D417/12;C07F7/10;C07K;(IPC1-7):A61K31/554;C07K5/065;C07K5/087;A61K38/05;A61K38/06 主分类号 A61K
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