发明名称 |
SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF |
摘要 |
Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, X, Y, and n are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor functio n or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
|
申请公布号 |
CA2496175(A1) |
申请公布日期 |
2004.03.04 |
申请号 |
CA20032496175 |
申请日期 |
2003.08.12 |
申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
THOMSON, DAVID S.;BEKKALI, YOUNES;WANG, JI;GILMORE, THOMAS A.;SPERO, DENICE MARY;TAKAHASHI, HIDENORI |
分类号 |
A61P3/10;A61P29/00;C07D215/12;C07D215/14;C07D405/04;C07D405/12;C07D409/04;(IPC1-7):C07D215/12;C07D401/04;C07D401/12;A61K31/47;A61K31/470 |
主分类号 |
A61P3/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|