发明名称 |
METHOD FOR IDENTIFICATION OF PROTEINS FROM INTRACELLULAR BACTERIA |
摘要 |
The present invention relates to a novel combination of methods that enables identification of proteins secreted from intracellular bacteria regardless of the secretion pathway. The invention further provides proteins that are identified by these methods. Secreted proteins are known to be suitable candidates for inclusion in immunogenic compositions and/or diagnostic purposes. The invention also provides peptide epitopes (T-cell epitopes) from the identified secreted proteins, as well as nucleic acid compounds that encode the proteins. The invention further comprises various applications of the proteins or fragments thereof, such as pharmaceutical and diagnostic applications. |
申请公布号 |
WO02082091(A3) |
申请公布日期 |
2004.03.04 |
申请号 |
WO2002DK00234 |
申请日期 |
2002.04.09 |
申请人 |
SHAW, ALLAN, CHRISTIAN;VANDAHL, BRIAN, BERG |
发明人 |
SHAW, ALLAN, CHRISTIAN;VANDAHL, BRIAN, BERG |
分类号 |
G01N33/53;A61K31/7088;A61K38/00;A61K39/00;A61K39/118;A61K39/395;A61K48/00;A61P7/02;A61P15/00;A61P27/02;A61P31/04;C07K14/295;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;C12Q1/37;C12R1/01;G01N33/483;G01N33/569;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|