发明名称 |
Method of constructing vectors for homologous recombination directed mutagenesis |
摘要 |
The present invention provides a novel vector system and thereby a novel method for the simplified construction of recombinant vectors for directed mutagenesis. Said vector system is used to modify the eukaryotic genome, particularly of embryonic stem cells, at precise and predefined loci by the means of homologous recombination. Further more, said system finds its usage in the generation of new strategies for gene therapy and in the generation of genetically modified higher eukaryotic organisms.
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申请公布号 |
US2004043487(A1) |
申请公布日期 |
2004.03.04 |
申请号 |
US20030636822 |
申请日期 |
2003.08.06 |
申请人 |
NEHLS MICHAEL;WATTLER SIGRID |
发明人 |
NEHLS MICHAEL;WATTLER SIGRID |
分类号 |
A61K48/00;C12N15/90;(IPC1-7):C12N15/74;C12N15/87 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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