发明名称 |
Recombinant terminal deoxynucleotidyl transferase with improved functionality |
摘要 |
Truncated terminal deoxynucleotidyl transferase (TdT) derivative from calf thymus, characterized in that the derivative in comparison to the native TdT is N-terminally truncated by up to 161 amino acids and has a 20- to 30-fold higher enzyme activity in solutions containing Co<2+> ions, and its recombinant production and use.
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申请公布号 |
US2004043396(A1) |
申请公布日期 |
2004.03.04 |
申请号 |
US20030406136 |
申请日期 |
2003.04.03 |
申请人 |
MUELLER RAINER;PAJATSCH MARKUS;CURDT INGO;SOBEK HARALD;SCHMIDT MANFRED;SUPPMANN BERNHARD;SONN KIRSTEN;SCHNEIDINGER BERND |
发明人 |
MUELLER RAINER;PAJATSCH MARKUS;CURDT INGO;SOBEK HARALD;SCHMIDT MANFRED;SUPPMANN BERNHARD;SONN KIRSTEN;SCHNEIDINGER BERND |
分类号 |
C12N15/09;C12N9/12;C12N15/54;C12Q1/48;(IPC1-7):C12Q1/68;C07H21/04;C12N9/10;C12P21/02;C12N5/06 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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