发明名称 |
EXPRESSION VECTORS ENCODING EPITOPES OF TARGET-ASSOCIATED ANTIGENS |
摘要 |
<p>The invention provides a nucleic acid construct encoding a housekeeping epitope derived from an antigen associated with a target cell. The construct can further include a second sequence encoding a housekeeping epitope or an immune epitope. The construct can be used as a vaccine against numerous kinds of target cells, including neoplastic cells and cells infected with an intracellular virus.</p> |
申请公布号 |
WO2004018666(A1) |
申请公布日期 |
2004.03.04 |
申请号 |
WO2003US26231 |
申请日期 |
2003.08.19 |
申请人 |
MANNKIND CORPORATION |
发明人 |
SIMARD, JOHN, J., L.;LEI, XIANG-DONG;DIAMOND, DAVID, C. |
分类号 |
A61K38/00;A61K39/00;A61K39/12;C07H21/04;C07K14/47;C07K14/74;C12N9/02;C12N15/74;C12N15/85;G01N33/68;G01R1/04;(IPC1-7):C12N15/00;C12N15/63;A61K31/70;C12N15/09 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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