发明名称 DERIVATIVES OF 3-HYDROXY-4-(CYCLYL-ALKYLAMINOALKYL)-5-PHENYL-1H-PYRAZOLE AS ANTAGONISTS OF THE GONADOTROPIN RELEASING HORMONE (GNRH) FOR USE IN THE TREATMENT OF SEX HORMONE RELATED CONDITIONS, SUCH AS PROSTATIC OF UTERINE CANCER
摘要 The invention relates to a group of novel pyrazole compounds of Formula (I): wherein: R<1>, R<2>, R<3>, M and R<5> are as defined in the specification, which are useful as gonadotrophin releasing hormone antagonists. The invention also relates to pharmaceutical formulations of said compounds, methods of treatment using said compounds and to processes for the preparation of said compounds.
申请公布号 WO2004017961(A2) 申请公布日期 2004.03.04
申请号 WO2003GB03633 申请日期 2003.08.19
申请人 ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BIRD, THOMAS, GEOFFREY, COLERICK;HERDEMANN, MATTHIAS, FERDINAND;MAUDET, MICKAEL, LOUIS, PIERRE 发明人 BIRD, THOMAS, GEOFFREY, COLERICK;HERDEMANN, MATTHIAS, FERDINAND;MAUDET, MICKAEL, LOUIS, PIERRE
分类号 A61K31/4155;A61K31/4196;A61K31/4439;A61K31/4725;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61K31/541;C07D231/20;C07D231/22;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D487/08;C07D491/04;C07D519/00 主分类号 A61K31/4155
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