发明名称 |
TROPICAL FORMULATION COMPRISING AT LEAST 5% OF METRONIDAZOLE IN WHITE PETROLATUM AND ITS USE IN THE ANAL AND RECTAL REGION |
摘要 |
A topical composition comprises at least 5-wt % metronidazole or a pharmacologically acceptable derivative thereof in a non-aqueous vehicle. The composition may be used in the treatment of conditions of the colon, rectum, anorectum and perianal region, in particular inflammatory bowel disease and perianal Crohn's disease. The composition also relieves pain and inflammation and promotes healing of the colon, rectum, and anorectum and perianal region following surgical operations. One advantage of the composition is that topical administration of metronidazole results in a primarily local effect and thus side effects observed from systemic administration are avoided. |
申请公布号 |
WO2004017962(A2) |
申请公布日期 |
2004.03.04 |
申请号 |
WO2003GB03692 |
申请日期 |
2003.08.22 |
申请人 |
S.L.A. PHARMA AG;ARMSTRONG, DAVID, NIGEL |
发明人 |
ARMSTRONG, DAVID, NIGEL |
分类号 |
A61K9/00;A61K31/245;A61K31/4164;A61K45/06;A61K47/06;A61P1/04;A61P17/02;A61P31/04 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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