DGAT INHIBITOR

摘要

PROBLEM TO BE SOLVED: To provide a DGAT (diacylglycerol acyltransferase) inhibitor containing a phosphonic acid diester derivative. SOLUTION: The DGAT inhibitor comprises the phosphonic acid diester represented by general formula [wherein R1is a phenyl group or a halogen-substituted phenyl group; R2is a hydrogen atom, a lower alkyl group, a carboxyl group, a lower alkoxycarbonyl group, a cyano group, a lower alkylcarbamoyl group, N,N-di-lower alkylcarbamoyl group or a pyrrolidinocarbonyl group; R3is a lower alkyl group] as an active ingredient. COPYRIGHT: (C)2004,JPO