| 发明名称 |
ANTI-HUMAN OVARIAN CANCER -ANTI-CD3 BISPECIFIC ANTIBODY |
| 摘要 |
<p>The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.</p> |
| 申请公布号 |
EP1394253(A1) |
申请公布日期 |
2004.03.03 |
| 申请号 |
EP20020734983 |
申请日期 |
2002.05.23 |
| 申请人 |
INSTITUTE OF GENETICS AND DEVEL. BIOL., CAS;BEIJING ABT GENETIC ENGINEERING TECHNOLOGY CO., LTD.;DONGGUANG HAOFA BIOTECHNOLOGY DEVELOPMENTAL CO. LTD |
发明人 |
HUANG, HUALIANG;JIANG, XIN;FANG, MIN;FENG, JIE;ZHOU, PING;YU, XIAOCONG;LIN, QING |
| 分类号 |
A61K39/395;A61P35/00;C07K16/28;C07K16/30;C07K16/46;C07K19/00;C12N15/13;C12N15/62;C12N15/63;C12P21/08;(IPC1-7):C12N15/13 |
主分类号 |
A61K39/395 |
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