MEANS AND METHODS FOR IDENTIFYING GENES AND PROTEINS INVOLVED IN THE PREVENTION AND/OR REPAIR OF A REPLICATION ERROR

摘要

The invention enables a person skilled in the art to determine whether a product of a gene is involved in the prevention of a mutation. Identified genes can be used to develop diagnostic tools or used as a target for drug development to manipulate cells on the basis of the presence or absence of function of this gene. Since DNA instability is one of the reasons for rapid tumor progression, gene therapy with products of such genes may be used to treat cancer.