发明名称 Method of increasing the efficacy of antibiotics by compexing with cyclodextrins
摘要 The present invention provides methods of increasing the biological activity of a bioactive agent by complexing the bioactive agent with a complexing agent. In one preferred embodiment, the bioactive agent is an antibiotic and the complexing agent is a cyclodextrin. However, the invention may be extended to include any drugs as bioactive agents. In certain preferred embodiments, the bioactive agent fits into a hydrophobic core of a complexing agent.
申请公布号 US6699505(B2) 申请公布日期 2004.03.02
申请号 US20010981655 申请日期 2001.10.17
申请人 MASSACHUSETTS INSTITUTE OF TECHNOLOGY 发明人 SHASTRI VENKATRAM R.;YUE ISAAC;HILDGEN PATRICE;SINISTERRA RUBEN DARIO;LANGER ROBERT
分类号 A61K31/155;A61K31/65;A61K31/70;A61K47/48;(IPC1-7):A61K9/14 主分类号 A61K31/155
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