发明名称 |
Method of increasing the efficacy of antibiotics by compexing with cyclodextrins |
摘要 |
The present invention provides methods of increasing the biological activity of a bioactive agent by complexing the bioactive agent with a complexing agent. In one preferred embodiment, the bioactive agent is an antibiotic and the complexing agent is a cyclodextrin. However, the invention may be extended to include any drugs as bioactive agents. In certain preferred embodiments, the bioactive agent fits into a hydrophobic core of a complexing agent.
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申请公布号 |
US6699505(B2) |
申请公布日期 |
2004.03.02 |
申请号 |
US20010981655 |
申请日期 |
2001.10.17 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
SHASTRI VENKATRAM R.;YUE ISAAC;HILDGEN PATRICE;SINISTERRA RUBEN DARIO;LANGER ROBERT |
分类号 |
A61K31/155;A61K31/65;A61K31/70;A61K47/48;(IPC1-7):A61K9/14 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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