发明名称 |
Antimicrobial agents diagnostic reagents, and vaccines based on unique apicomplexan parasite components |
摘要 |
This invention relates uses of components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on the components and their inhibitors.
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申请公布号 |
US6699654(B1) |
申请公布日期 |
2004.03.02 |
申请号 |
US19980103331 |
申请日期 |
1998.06.23 |
申请人 |
MCLEOD RIMA L. W.;ROBERTS CRAIG W.;ROBERTS FIONA;JOHNSON JENNIFER J.;METS LAURENS |
发明人 |
MCLEOD RIMA L. W.;ROBERTS CRAIG W.;ROBERTS FIONA;JOHNSON JENNIFER J.;METS LAURENS |
分类号 |
C12N9/88;G01N33/50;(IPC1-7):C12Q1/68;G01N33/53 |
主分类号 |
C12N9/88 |
代理机构 |
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代理人 |
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地址 |
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