摘要 |
A method is provided for sterilizing fluids using bolus dosing of a flui d, stretching of the bolus of fluid into a membrane, such as a thin or ultra-th in film, and subsequent irradiation of the individual fluid membranes which are then recollected after sterilization. A system is provided whereby a fluid moves along a defined pathway in traditional bolus flow where each bolus of fluid is interspersed with a bolus of gas. The bolus of fluid, for example from a patient or other sample , moves along the flow path and the width of the flow path is gradually increased until the fluid bolus is stretched (without breaking) to form a thin fluid membrane which can be completely panned using irradiation (such as ultraviolet irradiation) to sterilize the each bolus which has been stretched into a membrane. After sterilization the width of the flow path is gradually narrowed to a sufficient sized such that the bolu s returns to a sufficient size to be collected, typically when it forms a small droplet. The collected portions are recombined thereby rendering the original fluid sample complete ly sterilized for subsequent reintroduction into a patient or other use.</SDOAB >
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