发明名称 |
Tek antagonists |
摘要 |
A polypeptide comprising a fragment of a Receptor Tyrosine Kinase (RTK)- Tek (which is also called Tie2 and ork) extracellular domain, wherein the fragment lacks all or part of the refion containing fibronectin type III (FNIII) motifs and wherein the polypeptide retains the ability to bind at least one Tek ligand.
|
申请公布号 |
NZ516258(A) |
申请公布日期 |
2004.02.27 |
申请号 |
NZ20000516258 |
申请日期 |
2000.06.07 |
申请人 |
IMMUNEX CORPORATION |
发明人 |
CERRETTI, DOUGLAS PAT;BORGES, LUIS GHIRA;FANSLOW,WILLIAM CHRISTIAN |
分类号 |
C12N15/09;A61K31/138;A61K31/17;A61K31/196;A61K31/198;A61K31/255;A61K31/337;A61K31/4164;A61K31/475;A61K31/513;A61K31/519;A61K31/555;A61K31/7048;A61K31/7068;A61K33/24;A61K38/00;A61K38/21;A61K38/22;A61K38/43;A61K39/395;A61K45/00;A61P27/02;A61P35/00;C07K14/705;C07K14/71;C07K16/28;C07K19/00;C12N5/10;C12N15/12;C12P21/08;(IPC1-7):C12N15/12;G01N33/68;A61K38/17 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|