发明名称 SUBSTITUTED AZOLE ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD.
摘要 <p>(formula I); wherein Q is C or N; R2a, R2b, R2c, X1 to X7, R1, R2, R3, R3a, R4, A, Y, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents. The present invention further provides a method for treating obesity and dyslipidemia in mammals including humans through simultaneous inhibition of peroxisome proliferator activated receptor-gamma (PPARgamma) and stimulation of peroxisome proliferator activated receptor-alpha (PPARalpha).</p>
申请公布号 MXPA03010997(A) 申请公布日期 2004.02.27
申请号 MX2003PA10997 申请日期 2002.05.23
申请人 BRISTOL-MYERS COMPANY 发明人 HAO ZHANG
分类号 A61K31/137;A61K31/138;A61K31/155;A61K31/192;A61K31/198;A61K31/216;A61K31/22;A61K31/277;A61K31/357;A61K31/365;A61K31/40;A61K31/401;A61K31/403;A61K31/4035;A61K31/404;A61K31/41;A61K31/4168;A61K31/4178;A61K31/4184;A61K31/422;A61K31/427;A61K31/4365;A61K31/4418;A61K31/4422;A61K31/445;A61K31/4453;A61K31/455;A61K31/47;A61K31/517;A61K31/519;A61K31/55;A61K31/616;A61K31/64;A61K31/675;A61K38/28;A61K38/55;A61K45/00;A61P1/00;A61P1/04;A61P1/16;A61P3/04;A61P3/06;A61P3/10;A61P5/50;A61P7/02;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P11/00;A61P13/08;A61P15/00;A61P17/06;A61P19/10;A61P29/00;A61P35/00;A61P43/00;C07D413/12;C07D413/14;C07D417/14;(IPC1-7):A61K31/422 主分类号 A61K31/137
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