发明名称 THIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES.
摘要 The present invention provides a compound of formula I: or a pharmaceutically acceptable derivative thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3, Aurora2, and Syk mammalian protein kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatement of various protein kinase mediated disorders.
申请公布号 MXPA03010961(A) 申请公布日期 2004.02.27
申请号 MX2003PA10961 申请日期 2002.05.23
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 EDMUND HARRINGTON
分类号 A61K31/343;A61K31/403;A61K31/407;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K38/00;A61K39/395;A61K47/48;A61P35/00;A61P43/00;C07D405/06;C07D405/12;C07D405/14;C07D417/04;C07D417/14;C07D487/04;C07D487/10;C07D521/00;C07F7/18;C07F9/6561;C07K5/02;C07K7/02;C07K7/06;(IPC1-7):A61K31/427 主分类号 A61K31/343
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