| 摘要 |
<p>The invention relates to a process for the preparation of leukotriene antagonists corresponding to the formula I and the sodium salts thereof, wherein HET is 7-chloroquinolin-2-yl or 6,7-difluoroquinolin-2-yl, process which supposes : reacting the dilithium dianion of 1-(mercapto-methyl)cyclopropane acetic acid with a compound of formula (II), wherein HET is as defined above, and L is either arylsulfonyl or alkylsulfonyl. The invention relates to dicyclohexylamine salt of a compound of formula (I), to an intermediate of formula (II) and to a 1-(mercaptomethyl) cyclopropane acetic acid intermediate.</p> |
