发明名称 |
Method for treating diabetes |
摘要 |
The invention regards a screening method for screening for modulators of the expression of hnf4alpha from the hnf4alpha P2 promoter region, which method comprises the steps of obtaining a transcription reporter system comprising a nucleotide construct comprising a reporter gene under control of the hnf4alpha P2 promoter region corresponding to nucleotide 1 to 1447 of the sequence shown in the Sequence listing as SEQ ID No. 1 or a fragment thereof, contacting the transcription reporter system with a putative modulator and assaying for a change in the level of expression of the reporter gene.
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申请公布号 |
US2004038219(A1) |
申请公布日期 |
2004.02.26 |
申请号 |
US20020228368 |
申请日期 |
2002.08.13 |
申请人 |
FERNANDEZ SILVIA BOJ;HANSEN TORBEN;FREDERIKSEN SARA KRISTINE;JENSEN MARIA LAJER;PEDERSEN OLUF BORBYE;PARRIZAS MARCELINA;MAESTRO MIGUEL ANGEL;LEBL JAN;PRUHOVA STEPANKA;FERRER JORGE PEDRO |
发明人 |
FERNANDEZ SILVIA BOJ;HANSEN TORBEN;FREDERIKSEN SARA KRISTINE;JENSEN MARIA LAJER;PEDERSEN OLUF BORBYE;PARRIZAS MARCELINA;MAESTRO MIGUEL ANGEL;LEBL JAN;PRUHOVA STEPANKA;FERRER JORGE PEDRO |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;A61K31/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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地址 |
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