发明名称 |
Pyrazolecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them |
摘要 |
N-Piperidino-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethylpyrazole-3-carboxamide and its salts and solvates are powerful antagonists of the CB1 cannabinoid receptors. They are prepared by reacting a functional derivative of 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethylpyrazole-3-carboxylic acid with 1-aminopiperidine, optionally followed by salification.
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申请公布号 |
US2004039024(A1) |
申请公布日期 |
2004.02.26 |
申请号 |
US20030455220 |
申请日期 |
2003.06.05 |
申请人 |
BARTH FRANCIS;CAMUS PHILIPPE;MARTINEZ SERGE;RINALDI MURIELLE |
发明人 |
BARTH FRANCIS;CAMUS PHILIPPE;MARTINEZ SERGE;RINALDI MURIELLE |
分类号 |
A61K31/415;A61K31/454;A61P3/00;A61P3/04;A61P25/00;A61P25/18;A61P25/28;A61P25/32;A61P25/34;A61P43/00;C07C69/738;C07C251/80;C07D231/14;(IPC1-7):A61K31/454;C0743/02 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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