发明名称 COMPOSITIONS AND METHODS FOR TREATING RAGE-ASSOCIATED DISORDERS
摘要 Fusion proteins comprising a Receptor for Advanced Glycation End Products Ligand Binding Element (RAGE-LBE) and an immunoglobulin element are disclose d. Also disclosed are fusion proteins comprising a RAGE-LBE and a dimerization domain. Also disclosed are nucleic acids encoding such fusion proteins and methods for using disclosed nucleic acids and proteins to, for example, trea t RAGE-related disorders. Additional compositions and methods are also disclos ed.
申请公布号 CA2495663(A1) 申请公布日期 2004.02.26
申请号 CA20032495663 申请日期 2003.08.18
申请人 WYETH;IMPERIAL COLLEGE INNOVATIONS LIMITED 发明人 LARSEN, GLENN;FELDMAN, JEFFREY L.;FOXWELL, BRIAN JOHN MAURICE;TREPICCHIO, WILLIAM L.;FELDMANN, MARC;BRENNAN, FIONULA MARY;CLANCY, BRIAN;PITTMAN, DEBRA D.
分类号 C07K14/705;(IPC1-7):C12N15/62;A61K31/519;A61K38/17;A61K39/395;A61K45/00;C07K16/28;C07K19/00;C12N15/12;C12N15/13;C12P21/02;C12Q1/02;G01N33/566 主分类号 C07K14/705
代理机构 代理人
主权项
地址