COMPOSITIONS AND METHODS FOR TREATING RAGE-ASSOCIATED DISORDERS
摘要
Fusion proteins comprising a Receptor for Advanced Glycation End Products Ligand Binding Element (RAGE-LBE) and an immunoglobulin element are disclose d. Also disclosed are fusion proteins comprising a RAGE-LBE and a dimerization domain. Also disclosed are nucleic acids encoding such fusion proteins and methods for using disclosed nucleic acids and proteins to, for example, trea t RAGE-related disorders. Additional compositions and methods are also disclos ed.
申请公布号
CA2495663(A1)
申请公布日期
2004.02.26
申请号
CA20032495663
申请日期
2003.08.18
申请人
WYETH;IMPERIAL COLLEGE INNOVATIONS LIMITED
发明人
LARSEN, GLENN;FELDMAN, JEFFREY L.;FOXWELL, BRIAN JOHN MAURICE;TREPICCHIO, WILLIAM L.;FELDMANN, MARC;BRENNAN, FIONULA MARY;CLANCY, BRIAN;PITTMAN, DEBRA D.