Human frezzled-like protein

摘要

The present invention relates to a novel HFLP protein which is a member of the frizzled family. In particular, isolated nucleic acid molecules are provided encoding the human HFLP protein. HFLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of HFLP activity. Also provided are diagnostic methods for detecting cell growth and differentiation-related disorders and therapeutic methods for treating cell growth and differentiation-related disorders.