MODULATION OF ANGIOGENESIS THROUGH TARGETING OF CYSTEINE OXYGENASE ACTIVITY
摘要
The invention provides methods and compositions for modulating angiogenesis in a subject. The methods of modulating angiogenesis in a subject include administering to the subject a modulator of N-terminal cysteine oxygenase activity. The invention also provides a method of identifying such a modulator and a method of in vitro screening for modulators of N-terminal cysteine oxygenase activity. Additionally, the invention provides a method of treating an angiogenesis-related disorder.
申请公布号
WO03080000(A3)
申请公布日期
2004.02.26
申请号
WO2003US09062
申请日期
2003.03.21
申请人
CALIFORNIA INSTITUTE OF TECHNOLOGY;KWON, YONG, TAE;DAVYDOV, ILIA, V.;HU, RONG-GUI;DU, FANGYONG;VARSHAVSKY, ALAXENDER