发明名称 |
FGF-AFFINITY CHROMATOGRAPHY |
摘要 |
The present invention relates to a method and apparatus for isolating anticoagulant heparin or heparan sulfate by binding the anticoagulant heparin or anticoagulant heparan sulfate onto an affinity matrix and separating the non-bound material from the bound material. The affinity matrix is made of a fibroblast growth factor immobilized on a support. The invention also relates to a method and composition for neutralizing anticoagulant catalyzed by heparin, a heparin mimic, or a heparin derivative, by contacting heparin, a heparin mimic, or a heparin derivative with a fibroblast growth factor. |
申请公布号 |
WO0242336(A3) |
申请公布日期 |
2004.02.26 |
申请号 |
WO2001US43817 |
申请日期 |
2001.11.21 |
申请人 |
THE TEXAS A & M UNIVERSITY SYSTEM |
发明人 |
MCKEEHAN, WALLACE, L.;LUO, YONGDE |
分类号 |
C12N15/09;A61K38/00;A61K38/22;A61P7/02;A61P39/00;B01D15/08;B01J20/24;B01J20/34;C07K14/50;C08B37/00;C08B37/10;C12P21/02;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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