The present invention relates to novel amphipathic peptide-conjugated oligomeric compounds and to methods of making and using such compounds. The invention further relates to methods of enhancing the cellular uptake of oligomeric compounds comprising conjugating the compounds to amphipathic moieties such as amphipathic peptides.
申请公布号
WO2004016274(A2)
申请公布日期
2004.02.26
申请号
WO2003US25567
申请日期
2003.08.15
申请人
ISIS PHARMACEUTICALS, INC.;MANOHARAN, MUTHIAH;MAIER, MARTIN, A.
