摘要 |
A method of determining whether a subject is suffering from or at risk for developing a liver disease. The method includes providing a sample from the subject and determining a GADD45beta expression level or a GADD45beta activity level in the sample. If the GADD45beta expression level or the GADD45beta activity level in the sample is lower than that in a sample from a normal subject, it indicates that the subject is suffering from or at risk for developing a liver disease. Also disclosed are a method of identifying a compound for treating a liver disease and a method of treating such a disease. |