PYRAZOLE DERIVATIVES AS HIV REVERSE TRANSCRIPTASE INHIBITORS.

摘要

The invention is concerned with novel pyrazole derivatives, a process for their manufacture, pharmaceutical compositions and the use of such compounds in medicine. In particular, the compounds of formula I are inhibitos of the human immunodeficiency virus reverse transcriptase enzyme which is involved in viral replication. Consequently the compounds of this invention may be advantageously used as therapeutic agents for HIV mediated process. The invention describes novel compounds of formula I wherein R1, R2, R3 and A are as defined in the description; ethers of compounds of formula I as well as pharmaceutically acceptable salts of the foregoing.