发明名称 |
BMP-2 ESTROGEN RESPONSIVE ELEMENT AND METHODS OF USING THE SAME |
摘要 |
<p>The invention relates to an isolated nucleic acid corresponding to BMP-2 regulatory region, or a fragment thereof comprising an estrogen responsive element, vector comprising the same and cells, which comprises said vector. In another embodiment, the invention provides methods of identifying an estrogen agonist, antagonist and a therapeutic agent in another embodiment the invention provides methods of treating conditions which are associated with estrogen insufficiency or with lack of response to external estrogen or agonists thereof.</p> |
申请公布号 |
WO2004016639(A1) |
申请公布日期 |
2004.02.26 |
申请号 |
WO2003US23271 |
申请日期 |
2003.08.18 |
申请人 |
WYETH;BODINE, PETER, VAN NEST;GAZIT, DAN |
发明人 |
BODINE, PETER, VAN NEST;GAZIT, DAN |
分类号 |
A61K48/00;A61P19/08;C07H21/04;C07K14/51;C12N5/08;C12N15/63;C12N15/85;C12N15/86;C12Q1/68;(IPC1-7):C07H21/04 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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