LOCALLY IMPLANTABLE PHARMACEUTICAL PREPARATION OF ANTICANCER AGENT CONTAINING OSMOTIC AGENT

摘要

PURPOSE: Provided is a locally implantable pharmaceutical preparation of anticancer agent containing an osmotic agent. Therefore, its drug release is controlled and its cytotoxicity is increased. CONSTITUTION: A locally implantable pharmaceutical preparation of anticancer agent is characterized in that a pharmaceutical composition consisting of nitrosourea based anticancer agents and biodegradable polymers is added with 1-50 wt.% of an osmotic agent selected from salt, saccharides and saccharide mixtures.