PENTAFLUOROSULFUR-SUBSTITUTED BENZIMIDAZOLE COMPOUND AND METHOD FOR PRODUCING THE SAME

摘要

PROBLEM TO BE SOLVED: To produce a pentafluorosulfur-substituted benzimidazole compound useful as a physiologically active substance from an amino-substituted aryl(sulfur-trifluoride) more efficiently than by conventional methods. SOLUTION: This method for producing a compound of formula (4H)[W is a divalent group represented by formula: NH-C(Q)=N, wherein the direction of the divalent group is not limited; Q is H or the like] is characterized by cyclizing a compound of formula (3H) with a cyclizing reactant of formula: QCY1Y2Y3 (Y1, Y2, and Y3are each independently ORD, or the like; or two of Y1, Y2, and Y3may together form =O or the like). COPYRIGHT: (C)2004,JPO