发明名称 |
NEW OLIGOMERIC CONJUGATES LIABLE TO TRANSFER BIOLOGICAL MOLECULES INTO CELLS |
摘要 |
<p>The invention relates to a positively charged oligomeric conjugate, containing an oligomer with a polymerization degree (PD) from 5 to 50, preferably 10 to 40 and more preferably 20, formed from monomeric components having free NH3<+> in a number equal to or higher than 50 % of the polymerization degree. In particular, the invention provides new oligomeric conjugates of histidylated oligolysine liable to allow the transfer of oligonucleotides, peptides and oligosides into cells.</p> |
申请公布号 |
EP1135481(B1) |
申请公布日期 |
2004.02.25 |
申请号 |
EP19990959296 |
申请日期 |
1999.11.22 |
申请人 |
I.D.M. IMMUNO-DESIGNED MOLECULES |
发明人 |
MIDOUX, PATRICK;PICHON, CHANTAL;BELLO-ROUFAI, MAHAJOUB;MONSIGNY, MICHEL |
分类号 |
C12N15/09;A61K31/7088;A61K38/00;A61K47/48;A61K48/00;A61P29/00;A61P31/12;A61P35/00;A61P37/00;A61P37/06;A61P37/08;C07K14/00;C08G69/02;C12N15/11;(IPC1-7):C12N15/11 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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