| 摘要 |
A system and methods for local intradermal treatment of a dermal injury carrying the risk of innoculation with an identified pathogen or pathogens carried by an identified vector is described. In one embodiment, the system includes a multidrug pharmaceutical composition specifically targeting the pathogen or pathogens known to be carried by the identified vector. The pharmaceutical composition is applied to a dermal patch, which is applied to the skin at the site of dermal injury. The pharmaceutical composition further includes an enhancer for facilitating the penetration and absorption of the pharmaceutical composition into the dermal layers. The pharmaceutical composition provides local, intradermal drug concentrations which are sufficient to substantially eradicate or inhibit a pathogen while it remains intradermally localized.
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