发明名称 Preparation of dialkylpyridylboranes.
摘要 The present invention relates to method for the preparation of dialkylpyridylboranes by reacting a pyridine Grignard reagent with an alkoxydialkylborane or a trialkylborane. The reaction can be conducted at a temperature ranging from about 0 DEG C to about 40 DEG C. The pyridine Grignard reagent is preferably prepared in situ by the reaction of a Grignard reagent (RMgX) and a halopyridine in a suitable solvent, such as tetrahydrofuran, followed by the addition of an alkoxydialkylborane or a trialkylborane to form a dialkylpyridylborane.
申请公布号 ZA200206778(B) 申请公布日期 2004.02.23
申请号 ZA20020006778 申请日期 2002.08.23
申请人 PFIZER PRODUCTS INC. 发明人 RIPIN, DAVID, HAROLD, BROWN
分类号 C07D213/24;C07F5/02 主分类号 C07D213/24
代理机构 代理人
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