The present invention provides a chimeric molecule including a base-pairing segment that binds specifically to a single-stranded nucleic acid molecule; and a moiety that modulates splicing or translation. The invention also provides a chimeric molecule including a base-pairing segment that binds specifically to a double-stranded nucleic acid molecule; and a peptide that modulates transcription, wherein the peptide comprises up to about one hundred amino acid residues.
申请公布号
WO0238738(A3)
申请公布日期
2004.02.19
申请号
WO2001US47523
申请日期
2001.11.09
申请人
COLD SPRING HARBOR LABORATORY;KRAINER, ADRIAN, R.;CARTEGNI, LUCA