摘要 |
Methods, processes and materials for the production and recovery of Tiacumicins produced by culturing a microorganism belonging to the species Dactylosporangium aurantiacum subspecies hamdenensis having the ability to produce and accumulate one or more Tiacumicin in a nutrient medium comprising a carbon source, a nitrogen source, trace elements such as inorganic salts, and an adsorbent, wherein said nitrogen source comprises fish powder, and wherein said Tiacumicin is produced in a yield greater than about 50 mg/L broth. |
申请人 |
OPTIMER PHARMACEUTICALS, INC.;SHUE, YOUE-KONG;DU, CHI-JEN, FRANK;CHIOU, MING-HIS;WU, MEI-CHIAO;CHEN, YUAN-TING;OKUMU, FRANKLIN, W.;DUFFIELD, JONATHAN, JAMES |
发明人 |
SHUE, YOUE-KONG;DU, CHI-JEN, FRANK;CHIOU, MING-HIS;WU, MEI-CHIAO;CHEN, YUAN-TING;OKUMU, FRANKLIN, W.;DUFFIELD, JONATHAN, JAMES |