发明名称 |
ANTIMICROBIAL CHARGED POLYMERS THAT EXHIBIT RESISTANCE TO LYSOMAL DEGRADATION DURING KIDNEY FILTRATION AND RENAL PASSAGE, COMPOSITIONS AND METHOD OF USE THEREOF |
摘要 |
Methods and compositions for treating or preventing microbial infection in mammals with sulfated polysaccharides wherein the polysaccharides have a degree of sulfation effective to enable maximal interaction of constituent sulfate groups with the microbe which causes the infection and wherein the sulfated polysaccharide is not substantially endocytosed or degraded by cell receptor binding in the mammal and thereby retains antimicrobial activity in vivo.
|
申请公布号 |
CA2495116(A1) |
申请公布日期 |
2004.02.19 |
申请号 |
CA20032495116 |
申请日期 |
2003.04.24 |
申请人 |
MONASH UNIVERSITY |
发明人 |
COMPER, WAYNE D. |
分类号 |
A61K31/715;A61K31/727;A61K31/737;A61P31/00;A61P31/04;A61P31/10;A61P31/12;(IPC1-7):A61K31/737 |
主分类号 |
A61K31/715 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|