| 发明名称 |
TYROSINE KINASE INHIBITORS |
| 摘要 |
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and n on- receptor type tyrosine kinases. The compounds of the instant invention posse ss a core structure that comprises an indole-sulfonamide moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
|
| 申请公布号 |
CA2493575(A1) |
申请公布日期 |
2004.02.19 |
| 申请号 |
CA20032493575 |
申请日期 |
2003.08.05 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DINSMORE, CHRISTOPHER J.;LINDSLEY, CRAIG W.;BERGMAN, JEFFREY M.;BESHORE, DOUGLAS C. |
| 分类号 |
A61K31/40;A61P25/00;C07D209/42;C07D401/12;C07D403/12;C07D405/12;C07D409/12;(IPC1-7):C07D409/12;C07D209/30;A61K31/404;A61K31/41;A61K31/416;A61K31/419;A61K31/443;A61K31/454;A61K31/537 |
主分类号 |
A61K31/40 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
