DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN CXC CHEMOKINE RECEPTOR 5(CXCR5)

摘要

The invention provides a human CXCR5 which is associated with the cancer diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases and diseases of the hematological systems. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cancer diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases and diseases of the hematological system The invention also features compounds which bind to and/or active or inhibit the activity of CXCR5 as well as pharmaceutical compositions comprising such compounds.