发明名称 |
3-IMINO-2-INDOLONES FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY |
摘要 |
<p>This invention is directed to indolone derivatives which are selective antagonists for the GalR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. This invention also provides a method of treating depression and/or anxiety in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GalR3 receptor antagonist.</p> |
申请公布号 |
WO2004014854(A1) |
申请公布日期 |
2004.02.19 |
申请号 |
WO2003US24867 |
申请日期 |
2003.08.07 |
申请人 |
SYNAPTIC PHARMACEUTICAL CORPORATION |
发明人 |
KONKEL, MICHAEL;WETZEL, JOHN, M.;TALISMAN, JAMIE |
分类号 |
C07D209/40;C07D401/04;(IPC1-7):C07D209/02;C07D209/44;C07D401/00;A61K31/40;A61K31/44 |
主分类号 |
C07D209/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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